case 25||Solution||Part 2

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The answer to the given question is “Osteopetrosis” also known as:

✅Marble bone disease
✅Albers-Schönberg disease

⏩On X-ray:

✅Thick, Dense, White Bone

•So called as ‘Marble Bone disease’
•Diffuse Osteosclerosis
•Cortical Thickening with obliteration of medullary canal
(As shown in picture)

✅Endobones sign (Bone within a bone sign)

✅Rugger Jersey Spine

•Spine looks like the ‘Jersey of a Rugby player’
•Alternating stripes of White & Black
(As shown in picture)

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# Case

A 50 year-old man presents to his physician with hematuria. Renal biopsy demonstrates a focal necrotizing glomerulitis with crescent formation. The patient has a history of intermittent hemoptysis and intermittent chest pain of moderate intensity. A previous chest x-ray had demonstrated multiple opacities, some of which were cavitated. The patient also has chronic cold-like nasal symptoms.

Which of the following is the most likely diagnosis?

case 25 Solution Last Part

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The answer to the given question is “Osteopetrosis” also known as:

✅Marble bone disease
✅Albers-Schönberg disease

The above image shows:

⏩Erlenmeyer Flask Deformity

✅Diaphyseal constriction
✅Metaphyseal Flaring
✅Flattening of Distal Femoral Condyles

⏩Sandwich vertebrae

✅Upper & Lower border of vertebrae becomes sclerosed

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Identify the disease based on the symptoms and examination reports 🧐

The more you participate, more you learn💪

Comment in the box below⬇️⬇️

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case 26 Solution Part 1

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The answer to the given question is “Syphilitic aneurysm“ also known as ‘Luetic Aneurysm’

The following may be noted:

⏩Seen in Tertiary stage of Syphilis

⏩Causative agent:

✅Treponema pallidum (spirochete)

⏩Commonly seen in men

⏩Age group: 40-55 (Mean age: 50)

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A 70 year old male Kulsheen presents to your OPD with epigastric pain that typically starts about 30 minutes after meals and does not respond to antacids. He lost almost 3-4 kilograms over the last few weeks because he eats less for fear of pain. His past medical history is significant for hypertension, hyperlipidemia, coronary artery bypass grafting, and right-sided carotid endarterectomy. Upper gastrointestinal endoscopy does not reveal any abnormalities. The pathophysiology of this patient’s symptoms is most close to

case 26||Solution||Part 2

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The answer to the given question is “Syphilitic aneurysm“

⏩Gross Appearance:

✅Irregular intimal wrinkling of wall of aorta resembling “Tree-Bark”

‘Tree-Bark’ Appearance as shown in the picture

⏩Clinical Findings:

✅Aortic valve insufficiency

•Result in cardiac hypertrophy, the increase in the size of heart is called as cor bovinum/cow heart

(As shown in picture)

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