case 27 Solution Part 1

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The answer to the given question is “Paget’s Disease of Bone“ also known as ‘Osteitis deformans’

⏩It is High Turnover Bone Disease

⏩Usually begins after 40 years of age

⏩Prevalence increases with increasing age

⏩More common in whites

⏩Pathology:

Excess Osteoclastic Bone Resorption along with Excess Osteoblastic Bone formation
(Too much resorption & formation)

⬇️

Leads to Deformities & Potential Fractures



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case 27 || Solution || Part 2

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The answer to the given question is “Paget’s Disease of Bone“ also known as ‘Osteitis deformans’

⏩On X-ray:

⏹Osteoporosis Circumscripta:

✅Circumscribed Osteoporotic Patch due to Excessive Resorption

(As shown in Picture)

⏹Picture Frame Spine:

✅All 4 end plates (Anterior, Posterior, Superior, Inferior) are ‘Dense’ & ‘White’ resembling a “Picture Frame”

(As shown in Picture)

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case 27 || Solution || Part 2

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The answer to the given question is “Paget’s Disease of Bone“ also known as ‘Osteitis deformans’

⏩On X-ray:

⏹Cotton Wool Skull:

✅Thickened Outer Table of Skull

✅Excessive White Skull

✅’Cotton Wool Spots’ due to too much of formation

(As shown in Picture)

⏹’Blade of Grass Sign’ / ‘Flame Sign’ / ‘Advancing Wedge Sign’:

➡️Femur shows ‘Mixed Phase’

✅Excess White (due to too much Resorption)

✅Excess Black (due to too much Formation)

✅Excess Blackish Region is resembling a ‘Flame’ or ‘Blade of Grass’ or ‘Wedge’

(As shown in Picture)