What is the MOST common metastatic site of Wilms tumor?
Anonymous Quiz
64%
Lung
16%
Bone marrow
7%
Spleen
12%
Brain
A 10yr girl is referred to the Heme/onc unit after initial diagnosis of Wilms, tumor based on imaging studies. O/e , she is short stature, microcephaly, and has café-au-lait spots distributed on the trunk.
Of the following, the MOST likely diagnosis is
Of the following, the MOST likely diagnosis is
Final Results
12%
Diamond-Blackfan Anemia
10%
Dyskeratosis Congenita
59%
Fanconi anemia
16%
Shwachman-Diamond syndrome
3%
Cartilage hypoplasia
🔑Patients with Alport syndrome can't pee, can't see, can't hear.
It’s a Genetic defect of type IV collagen chains (component of the basement membrane of the kidneys, eye, and cochlea) → (glomerulonephritis)
-Keratoconus
-Nephritic syndrome
-Sensorineural hearing loss
It’s a Genetic defect of type IV collagen chains (component of the basement membrane of the kidneys, eye, and cochlea) → (glomerulonephritis)
-Keratoconus
-Nephritic syndrome
-Sensorineural hearing loss
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Refeeding syndrome
Refeeding syndrome is a condition caused by rapid reinitiation of normal nutrition in a chronically malnourished patient. It is characterized by metabolic derangements and organ dysfunction.
Pathophysiology
Very rapid increase in daily food intake in severely malnourished patients can cause massive insulin release → increased displacement of magnesium, potassium, and phosphate (shift from extracellular to intracellular) → ↓ phosphate, ↓ potassium, ↓ magnesium (serum levels)
Clinical features
• Neurological: seizures, ataxia, encephalopathy
• Cardiovascular: arrhythmias (e.g., tachycardia, torsades de pointes, cardiac arrest), edema
• Gastrointestinal: abdominal discomfort, bloating after meals
• Musculoskeletal: weakness, rhabdomyolysis
❗️Hypophosphatemia is the primary biochemical indicator of refeeding syndrome.
Refeeding syndrome is a condition caused by rapid reinitiation of normal nutrition in a chronically malnourished patient. It is characterized by metabolic derangements and organ dysfunction.
Pathophysiology
Very rapid increase in daily food intake in severely malnourished patients can cause massive insulin release → increased displacement of magnesium, potassium, and phosphate (shift from extracellular to intracellular) → ↓ phosphate, ↓ potassium, ↓ magnesium (serum levels)
Clinical features
• Neurological: seizures, ataxia, encephalopathy
• Cardiovascular: arrhythmias (e.g., tachycardia, torsades de pointes, cardiac arrest), edema
• Gastrointestinal: abdominal discomfort, bloating after meals
• Musculoskeletal: weakness, rhabdomyolysis
❗️Hypophosphatemia is the primary biochemical indicator of refeeding syndrome.
MEALS lead to Kwashiorkor: Malnutrition, Edema, Anemia, fatty Liver, Skin lesions.
Marasmus causes Muscle wasting but no edema.
Marasmus causes Muscle wasting but no edema.
CRASH and BURN:
Conjunctivitis, Rash, Adenopathy, Strawberry tongue, Hands and feet, and BURN (fever ≥ 5 days) are the most common features of Kawasaki disease.
Conjunctivitis, Rash, Adenopathy, Strawberry tongue, Hands and feet, and BURN (fever ≥ 5 days) are the most common features of Kawasaki disease.
The 6 A's of ataxia telangiectasia: ATM gene, Ataxia, spider Angiomas, and IgA deficiency and Alpha fetoprotein, AR
Forwarded from 𝐸𝑠𝑙𝑎𝑚 𝐸𝑡𝑎𝑦𝑒𝑏
A 2-year-old girl with a history of chronic constipation since birth is brought to the emergency room because of nausea and vomiting. Physical examination shows marked abdominaldistension.Abdominal radiography reveals distended bowel loops with a paucity of air in the rectum. A rectal biopsy shows an absence of ganglion cells.Which of the following is the most likely diagnosis?
Forwarded from 𝐸𝑠𝑙𝑎𝑚 𝐸𝑡𝑎𝑦𝑒𝑏
Select the most accurate diagnosis:-
Anonymous Quiz
6%
Acquired mega colon
8%
Colonic carcinoma
8%
Rectal polyp
6%
Rectal atresia
72%
Hirschsprung Disease
Forwarded from 𝐸𝑠𝑙𝑎𝑚 𝐸𝑡𝑎𝑦𝑒𝑏
Forwarded from 𝐸𝑠𝑙𝑎𝑚 𝐸𝑡𝑎𝑦𝑒𝑏
These are features of iron deficiency anemia except
Anonymous Quiz
7%
Microcytic hypochromatic
63%
Increase plasma transferrin saturation
20%
Increase total iron binding capacity
10%
Decrease serum iron and ferritin levels