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Popes from the Borgia family

The Borgias, also known as the Borjas, were a European papal family of Spanish origin that became prominent during the Renaissance. The family produced three popes of the Catholic Church:

Pope Callixtus III (born Alfons de Borja; 1378–1458) – served as pope from 8 April 1455 until his death on 6 August 1458[1]

Pope Alexander VI (born Rodrigo Lanzol Borgia; 1431–1503) – served as
pope from 11 August 1492 until his death on 18 August 1503; his maternal uncle was Pope Callixtus III[2]

Pope Innocent X[3] (born Giovanni Battista Pamphilj (or Pamphili); 1574–1655) – served as pope from 15 September 1644 until his death on 7 January 1655; he was the great-great-great-grandson of Pope Alexander VI, but his surname was not Borgia

Popes from the Conti family

The Conti di Segni (de Comitibus Signie, also known as Conti or De Comitibus for short) were an important noble family of medieval and early modern Italy originating in Segni, Lazio. Many members of the family acted as military commanders or ecclesiastical dignitaries, including many cardinals and four popes and one antipope.

During the Middle Ages, the Conti were notable, including four who became popes:

Pope Innocent III (1160 or 1161– 16 July 1216), born Lotario de' Conti, was the head of the Catholic Church from 8 January 1198 to his death in 1216.

Pope Gregory IX (1227–1241), born Ugolino di Conti

Pope Alexander IV (1254–1261), born Rinaldo di Conti

Pope Innocent XIII (1721–1724), born Michelangelo di Conti

Antipope Victor IV (1138), born Gregorio di Conti


http://www.newadvent.org/cathen/08013a.htm
http://www.newadvent.org/cathen/06796a.htm
http://www.newadvent.org/cathen/01287b.htm
http://www.newadvent.org/cathen/08023a.htm
http://www.newadvent.org/cathen/15411a.htm