Correct Answer - A
Ans. A. Idiopathic
[Ref: Neena Khanna Yale p. 61, 63]

Erythema multiforme
Most of the cases of erythema multiforme are idiopathic, but
amongst the causative agents Herpes simplex virus is the most
important cause.


Erythema multiforme is an acute, often self limited erutption
characterized by a distinctive clinical eruption, the hallmark of which is the Target lesion (Iris lesion or Bulle's eye lesion).

@dermatology_vid

Correct Answer - D
Ans. D. DNA repair defect
[Ref Rook's 4thie p. 78.12]

Xeroderma pigmentosa
Molecular defect:
Exposure to UV rays damages DNA due to production of convalent
linkages between adjacent pyrimidines (pyrimidine dimmers).

Normally the damaged DNA is repaired by excision and repair.

In xeroderma pigmentosa the repair of UV damaged DNA is defective.
It is an autosomal recessive disorder

@dermatology_vid

Correct Answer - A
Answer- A. Palpable purpura
Palpable purpura is essential for diagnosis.

Diagnosis is confirmed by presence of palpable purpura with normal
platelet count along with one or more of the following : abdominal
pain, arthralgia/arthritisand mesangial deposition of IgA.

@dermatology_vid

Correct Answer - A
Ans. is 'a' i.e., N. gonococci
Information in this question are ?
1. Gram negative diplococci.
2. Growth on modified Thayer-martin media.
o Neisseria gonorrhoeae is a gram negative diplococci and Thayermartin medium is the selective medium for gonococci.
Lab diagnosis of gonorrhea
Urethral discharge is the most important specimen.
Transport media
1. La It processing is to occur within 6 hrs ---> Stuart medium or A mies medium.
2. If processing is to occur > 6 hrs —> JEMBEC or Gono - Pak
system (media with self - contained CO2 -generating system).

Cluture media
1. In acute cases --> Chocolate agar or Muller - Hinton agar.
2. In chronic cases ---> Selective medium - Thayer martin medium.
Normally the diagnosis of gonorrhoea is made by isolating the organism in culture

@dermatology_vid

Correct Answer - B
Ans. is 'b' i.e., Bechet's syndrome
Criteria for diagnosis of Bechet's disease

Recurrent oral ulcer for at least 3 times in 12 months.
Plus any two of the followings :?
1. Recurrent genital ulcer.
2. Eye inflammation with loss of vision.
3. Characterstic skin lesion (erythema nodosum).
4. Positive pathergy test (skin prick test)

@dermatology_vid

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Correct Answer - D
Ans. D. DNA repair defect
[Ref Rook's 4thie p. 78.12]

Xeroderma pigmentosa
Molecular defect:

Exposure to UV rays damages DNA due to production of convalent
linkages between adjacent pyrimidines (pyrimidine dimmers).

Normally the damaged DNA is repaired by excision and repair.

In xeroderma pigmentosa the repair of UV damaged DNA is
defective.

It is an autosomal recessive disorder.

@dermatology_vid

Correct Answer - A
Ans. A. Remain constant throughout life time of a person
[Ref: IADVL text book of dermatology 3rd le p. 175 & Internet]
Langer's lines

Also called cleavage lines, is a term used to define the direction
within the human skin along which the skin has the least flexibility.

These lines correspond to the alignment of collagen fibers within the dermis.

Usually, a surgical cut is carried out in the direction of langer's lines,
and incisions made parallel to langer's lines generally heal better
and produce less scarring.

Directional changes of Langer's lines have been known to occur
within the course of a person's lifetime.

Sometimes the exact direction of these lines are unknown, because
in some regions of the body there are differences between different
individuals

@dermatology_vid

Correct Answer - B
Ans. B. Reverse Koebner's phenomenon


Annular orange skin lesions in a diabetic indicate towards granuloma annulare.

There have been few reports of disappearance of lesions after
biopsy in granuloma annulare.
This phenomenon is known as reverse Koebner's phenomenon.

@dermatology_vid

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Correct Answer - D
Ans. D. Lichen planus

LP is characterized by shiny, violaceous, flat-topped polygonal
papules which retain the skin lines.

White lines, known as Wickham's striae, may traverse the surface of
the papules.

Linear lesions often appear along scratch marks or in scars
(Koebner phenomenon).

In most cases, the papules eventually flatten after a 6 months to 2 yrs, often to be replaced by an area of hyperpigmentation.

@dermatology_vid