Evolution of B-CLL into diffuse
large B-cell lymphoma (Richter syndrome).

B-PLL

B-PLL

B-PLL

PB demonstrating hairy cells

BM with many hairy cells

Plasma cells. Note rouleaux

Plasma cells, one multinucleated

Plasmablast. with the lighter blue
cytoplasm with the indistinct hof and the slightly
eccentric nucleus with 2 distinct nucleoli

Proplasmacyte. The cytoplasm is
darker blue and the perinuclear hof is distinct. The
nucleus is eccentric and the nucleolus is partially masked
by the clumped chromatin

Flame cell. Associated with plasma
cells that are producing immunoglobulin A (IgA)

Mott cell (morula cell, grape cell).
Plasma cell containing multiple round globules of
immunoglobulin, which stain pink, colorless, or blue

ALL-L3 PB

ALL-L3 BM

PB film in splenic
lymphoma with villous lymphocytes.
The cells have small, inconspicuous
nucleoli. One has villous cytoplasm
and one is showing plasmacytoid
differentiation

PB film in the leukaemic
phase of follicular lymphoma. One
cell is very small with scanty
cytoplasm; the other is nucleolated
and has a deep, narrow cleft.

CML - PB

CML - BM

DYSERYTHROPOIESIS

DYSERYTHROPOIESIS