Classic triad of the hemochromatosis is : 1-cirrhosis.
2-secondary diabetes mellitus.
3-bronze skin
2-secondary diabetes mellitus.
3-bronze skin
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-H&E stain
-Deposits of coarse granular brown pigment are visible within the hepatocytes (examples indicated by blue circles).
- Further deposits also appear in portal tract macrophages (examples indicated by yellow circles).
-These deposits stained positive with the iron stain (prussian blue stain; not shown here), which leads to the diagnosis of hemochromatosis.
-Deposits of coarse granular brown pigment are visible within the hepatocytes (examples indicated by blue circles).
- Further deposits also appear in portal tract macrophages (examples indicated by yellow circles).
-These deposits stained positive with the iron stain (prussian blue stain; not shown here), which leads to the diagnosis of hemochromatosis.
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-A brown ring is visible in the periphery of the cornea (Kayser-Fleischer ring; green overlay).
-Kayser-Fleischer rings are typically seen in Wilson disease.
-Kayser-Fleischer rings are typically seen in Wilson disease.
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-Causes of renal papillary necrosis :
1-chronic analgesic abuse
2-Diabetes mellitus
3-Sickle cell trait or disease
4-Sever acute pyelonephritis
1-chronic analgesic abuse
2-Diabetes mellitus
3-Sickle cell trait or disease
4-Sever acute pyelonephritis
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